Publications by John Petkau
2018
Comparison of statistical approaches dealing with time-dependent confounding in drug effectiveness studies. Statistical Methods in Medical Research [Internet]. 2018;27 :1709-1722. http://journals.sagepub.com/doi/abs/10.1177/0962280216668554 .
2017
Identification of treatment responders based on multiple longitudinal outcomes with applications to multiple sclerosis patients. Statistics in Medicine. 2017;36:1862-1883. .
Evaluating the safety of beta-interferons in multiple sclerosis: A series of nested case-control studies. Neurology. 2017;88:2310-2320. .
On the application of statistical learning approaches to construct inverse probability weights in marginal structural Cox models: Hedging against weight-model misspecification. Communications in Statistics - Simulation and Computation. 2017;46:7668-7697. .
Bayesian analysis of pair-matched case-control studies subject to outcome misclassification. Statistics in Medicine. 2017;36:4196-4213. .
Effects of adherence to the first-generation injectable immunomodulatory drugs on disability accumulation in multiple sclerosis: a longitudinal cohort study. British Medical Journal Open [Internet]. 2017;7:ID e018612, 7 pages. https://bmjopen.bmj.com/content/7/9/e018612 .
2016
Comparison of statistical approaches for dealing with immortal time bias in drug effectiveness studies. American Journal of Epidemiology. 2016;184:857-858. .
Comparison of statistical approaches for dealing with immortal time bias in drug effectiveness studies. American Journal of Epidemiology. 2016;184:325-335. .
An adaptive clinical trials procedure for a sensitive subgroup examined in the multiple sclerosis context. Statistical Methods in Medical Research [Internet]. 2016;25:1330-1345. http://smm.sagepub.com/content/early/2013/04/01/0962280213480576 .
Association between the use of selective serotonin reuptake inhibitors and multiple sclerosis disability progression. Pharmacoepidemiology and Drug Safety. 2016;25:1150-1159. .
2015
Personalized activity index, a new safety monitoring tool for multiple sclerosis clinical trials. Multiple Sclerosis Journal – Experimental, Translational and Clinical [Internet]. 2015;1:1-15. http://mso.sagepub.com/content/1/2055217315577829 .
Beta-interferon exposure and onset of secondary progressive multiple sclerosis. European Journal of Neurology [Internet]. 2015;22:990–1000. http://onlinelibrary.wiley.com/doi/10.1111/ene.12698/abstract .
Predictors of disease activity in 857 patients with MS treated with interferon beta-1b. Journal of Neurology. TIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY: SPRINGER HEIDELBERG; 2015;262:2466-2471. .
Sample-size calculations for short-term proof-of-concept studies of tissue protection and repair in multiple sclerosis lesions via conventional clinical imaging. Multiple Sclerosis Journal. 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND: SAGE PUBLICATIONS LTD; 2015;21:1693-1704. .
A flexible mixed-effect negative binomial regression model for detecting unusual increases in MRI lesion counts in individual multiple sclerosis patients. Statistics in Medicine. 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY-BLACKWELL; 2015;34:2165-2180. .
Multiple sclerosis in older adults: the clinical profile and impact of interferon beta treatment. BioMed Research International. 410 PARK AVENUE, 15TH FLOOR, \#287 PMB, NEW YORK, NY 10022 USA: HINDAWI PUBLISHING CORPORATION; 2015;2015:ID451912, 11 pages. .
Further investigation of safety monitoring guidelines based on magnetic resonance imaging lesion activity in multiple sclerosis clinical trials. Multiple Sclerosis Journal [Internet]. 2015;21:101-104. http://msj.sagepub.com/content/early/2014/05/20/1352458514533846 .
2014
Association between beta-interferon exposure and hospital events in multiple sclerosis. Pharmacoepidemiology and Drug Safety. 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY-BLACKWELL; 2014;23:1213-1222. .
Defining the clinical course of multiple sclerosis: The 2013 revisions. Neurology. TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA: LIPPINCOTT WILLIAMS & WILKINS; 2014;83:278-286. .
Marginal structural Cox models for estimating the association between beta-interferon exposure and disease progression in a multiple sclerosis cohort. American Journal of Epidemiology. JOURNALS DEPT, 2001 EVANS RD, CARY, NC 27513 USA: OXFORD UNIV PRESS INC; 2014;180:160-171. .
Investigation of heterogeneity in the association between interferon beta and disability progression in multiple sclerosis: an observational study. European Journal of Neurology [Internet]. 2014;21:835–844. http://onlinelibrary.wiley.com/doi/10.1111/ene.12324/abstract .
Detection of unusual increases in MRI lesion counts in individual multiple sclerosis patients. Journal of the American Statistical Association [Internet]. 2014;109:119–132. http://amstat.tandfonline.com/doi/abs/10.1080/01621459.2013.847373 .
2013
Interferon beta and long-term disability in multiple sclerosis. JAMA Neurology. 515 N STATE ST, CHICAGO, IL 60654-0946 USA: AMER MEDICAL ASSOC; 2013;70:651-652. .
2012
Treatment with interferon beta for multiple sclerosis: reply. Journal of the American Medical Association. 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA: AMER MEDICAL ASSOC; 2012;308:1627-1628. .
MRI-based clinical trials in relapsing-remitting multiple sclerosis: new sample size calculations based on a longitudinal model. Multiple Sclerosis Journal. 2012;18:1600–1608. .
Natural, innate improvements in multiple sclerosis disability. Multiple Sclerosis Journal. 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND: SAGE PUBLICATIONS LTD; 2012;18:1412-1421. .
Association between use of interferon beta and progression of disability in patients with relapsing-remitting multiple sclerosis. Journal of the American Medical Association. 330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA: AMER MEDICAL ASSOC; 2012;308:247-256. .
Neutralizing antibodies to interferon beta-1b in multiple sclerosis: a clinico-radiographic paradox in the BEYOND trial. Multiple Sclerosis Journal. 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND: SAGE PUBLICATIONS LTD; 2012;18:181-195. .
MRI monitoring of immunomodulation in relapse-onset multiple sclerosis trials. Nature Reviews Neurology. 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA: NATURE PUBLISHING GROUP; 2012;8:13-21. .
A longitudinal model for magnetic resonance imaging lesion count data in multiple sclerosis patients. Statistics in Medicine [Internet]. 2012;31:449–469. http://onlinelibrary.wiley.com/doi/10.1002/sim.4394/abstract .
2011
Interferon β-1b–neutralizing antibodies 5 years after clinically isolated syndrome. Neurology [Internet]. 2011;77:835–843. http://www.neurology.org/content/77/9/835 .
The growing need for alternative clinical trial designs for multiple sclerosis. In Multiple Sclerosis Therapeutics. 4th ed. Cambridge: Cambridge University Press; 2011. pp. 253-260. .
Predictors of sexual desire disorders in women. The Journal of Sexual Medicine. 2011;8:742–753. .
Evaluation of safety monitoring guidelines based on MRI lesion activity in multiple sclerosis. Neurology [Internet]. 2011;77:2089–2096. http://www.neurology.org/content/77/24/2089 .
2010
Recommendations for clinical use of data on neutralising antibodies to interferon-beta therapy in multiple sclerosis. Lancet Neurology. 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA: ELSEVIER SCIENCE INC; 2010;9:740-750. .
Role of androgens in women's sexual dysfunction. Menopause. 75 YANAGINOBANBA NISHIIRU-MASUYA-CHO, SANJOU-DORI, NAKAGYOU-KU, KYOTO, 604-8111, JAPAN: JAPAN ENDOCRINE SOC; 2010;17:962-971. .
Does MRI lesion activity regress in secondary progressive multiple sclerosis?. Multiple Sclerosis [Internet]. 2010;16:434-442. http://msj.sagepub.com/content/early/2010/02/18/1352458509359726 .
2008
Intermediate highly active antiretroviral therapy adherence thresholds and empirical models for the development of drug resistance mutations. Journal of Acquired Immune Deficiency Syndromes [Internet]. 2008;47:397–399. http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:landingpage&an=00126334-200803010-00020 .
Magnetic resonance imaging as a surrogate outcome for multiple sclerosis relapses. Multiple Sclerosis [Internet]. 2008;14:770-778. http://msj.sagepub.com/content/early/2008/06/05/1352458507088104 .
Regression of new gadolinium enhancing lesion activity in relapsing-remitting multiple sclerosis. Neurology. AAN Enterprises; 2008;70:1092–1097. .
Ethics of placebo-controlled clinical trials in multiple sclerosis: a reassessment. Neurology [Internet]. 2008;70:1134–1140. http://www.neurology.org/content/70/13_Part_2/1134 .
2007
Seasonal confounding and residual correlation in analyses of health effects of air pollution. Environmetrics. Wiley Online Library; 2007;18:375–394. .
The impact of ongoing illicit drug use on methadone adherence in illicit drug users receiving treatment for HIV in a directly observed therapy program. Drug and Alcohol Dependence. Elsevier; 2007;89:306–309. .
2006
MRI T2 lesion burden in multiple sclerosis: A plateauing relationship with clinical disability. Neurology. AAN Enterprises; 2006;66:1384–1389. .
Liver test abnormalities in multiple sclerosis: Findings from placebo-treated patients. Neurology. AAN Enterprises; 2006;67:1291–1293. .
2005
Evaluation of asymptotic approximations for a two-stage Bernoulli bandit. Journal of Statistical Planning and Inference. Elsevier; 2005;130:133–148. .
Application of hidden Markov models to multiple sclerosis lesion count data. Statistics in Medicine. Wiley Online Library; 2005;24:2335–2344. .
Predicting gadolinium enhancement status in MS patients eligible for randomized clinical trials. Neurology. AAN Enterprises; 2005;65:1447–1454. .
2004
Longitudinal analyses of the effects of neutralizing antibodies on interferon beta-1b in relapsing/remitting multiple sclerosis. Multiple Sclerosis. 2004;10:715. .
Longitudinal analyses of the effects of neutralizing antibodies on interferon beta-1b in relapsing-remitting multiple sclerosis. Multiple Sclerosis. Sage Publications; 2004;10:126–138. .